Corpus callosum index correlates with brain volumetry and disability in multiple sclerosis patients
نویسندگان
چکیده
منابع مشابه
Optical Coherence Tomography and Corpus Callosum Index in Cognitive Assessment of Multiple Sclerosis Patients
Background: Multiple Sclerosis (MS) is a neurodegenerative disease of central nervous system. Different approaches have been developed to study MS progression and cognitive dysfunction as the major symptom of the disease. The current study compared Optical Coherence Tomography (OCT) and Corpus Callosum Index (CCI) for the early evaluation of cognitive dysfunction in MS patients. Objectives: T...
متن کاملCorpus callosum in multiple sclerosis.
A neuropathological study of 20 multiple sclerosis brains using celloidin-embedded slices was carried out to assess the extent of changes in the corpus callosum. Severe atrophy of the callosum was found in cases with marked hydrocephalus. Demyelination of the callosum varied in extent from slight involvement (with a few small plaques) to almost total myelin loss. A clinical history of mental de...
متن کاملCorpus Callosum deformation analysis in Multiple Sclerosis
Dans cet article, nous présentons une méthode de mesure des déformations volumiques du Corps Calleux (CC) consécutives à la Sclérose En Plaques (SEP). Une méthode de segmentation 3 D du volume d'intérêt basée sur les modèles déformables est proposée. Des mesures sont ensuite réalisées sur ce volume à partir d'Imagerie par Résonance Magnétique (IRM) cérébrales. La variabilité de la forme géométr...
متن کاملMyelin enhancement of Multiple sclerosis model with gold nanoparticles into the corpus callosum
Objective(s): With no substantial cost, we injected L-arginine into the rat’s corpus callosum (CC) to create animal model of multiple sclerosis (MS) and investigated the pre-injection effect of gold nanoparticles (GNPs). Materials and Methods: Adult male Wistar rat (250-300 g) was surgically cannulated at the CC, and after recovery it was injected L-arginine (3-200 µg/rat, intra-CC) once ...
متن کاملInfluence of Corpus Callosum Damage on Cognition and Physical Disability in Multiple Sclerosis: A Multimodal Study
BACKGROUND Corpus callosum (CC) is a common target for multiple sclerosis (MS) pathology. We investigated the influence of CC damage on physical disability and cognitive dysfunction using a multimodal approach. METHODS Twenty-one relapsing-remitting MS patients and 13 healthy controls underwent structural MRI and diffusion tensor of the CC (fractional anisotropy; mean diffusivity, MD; radial ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurosciences
سال: 2020
ISSN: 1658-3183
DOI: 10.17712/nsj.2020.3.20190093